Abstract

Specialized food products development, including biologically active additives (BAA), is one of the priority areas in the realization of the healthy eating program and the food and pharmaceutical industries development in the Russian Federation. A lot of attention is paid to the proof of effectiveness and functional orientation of the concerned foodstuff. Dietetic therapy with the use of BAA is considered to be the most available way to improve the modern man’s nutrition and health. The aim of this work was to develop and confirm specialized food products’ practical application through clinical trials and mass production organization. Specialized products for dietetic nutrition and protective diet such as BAA (“Energopan”, “Cleopanta”, “Green Star”) and the “Light mood” bar were developed. Methodological aspects of the new types of the specialized products’ creation were described. Prescription formulas with account taken of pharmacological characteristics of their active principles were scientifically proven. Regulated indices of nutrition value including recommended amount of consumption of the developed product and safety criteria that allowed establishing duration of realization were identified. Clinical trials of the specialized products were conducted: “Light mood” bar and the BAA “Green Star” were included in study groups’ ration and their biomedical measurements characterizing metabolic care were analyzed. Observational results allowed to recommend the “Light mood” bar for prophylaxis and treatment of the constipation in combination with other somatic diseases and the BAA “Green Star” for digestion health improvement in the function of energy absorbent and improvement of the overall level of metabolism. Developed products’ formulation and technology were tested under production conditions in the SPA “Yug” and the “Art-Life” company (Russia).

Keywords

prescription ingredients, biologically active additives, functional properties, effectiveness, clinical trials

REFERENCES

1. Vekovtsev A.A. and Solodilova A.A. Biologicheski aktivnye kompleksy i produkty funktsional'nogo pitaniya «Artlayf» v kompleksnoy terapii i profilaktike zabolevaniy. Rukodstvo po produktsii: spravochnoe posobie [Biologically active complexes and functional food products "Artlife" in the treatment and prevention of diseases. Instruction of the product: handbook]. Tomsk: Artlife Publ., 2013. 320 p.
2. Tutel'yan V.A. (ed.) Vitaminy i mikroelementy v klinicheskoy farmokologii [Vitamins and minerals in clinical pharmacology]. Moscow: Paleya Publ., 2001. 560 p.
3. Georgievskiy V.P., Komisarenko N.F., and Dmitruk S.E. Biologicheski aktivnye veshchestva lekarstvennykh rasteniy [Biologically active substances of medicinal plants]. Novosibirsk: Nauka Publ., 1990. 333 p.
4. Gichev Yu.Yu. Novoe rukovodstvo po mikronutrientologii (biologicheski aktivnye dobavki k pishche i zdorov'e cheloveka) [New Guide to biologically active additives to food and human health]. Moscow: Triada - Kh Publ., 2009. 304 p.
5. Gur'yanov Yu.G. Pantogematogen i spetsializirovannye produkty s ego ispol'zovaniem: novye tekhnologii, otsenka kachestva i effektivnosti [Pantogematogen and specialty products to its use of new technologies, evaluation of the quality and efficiency]. Kemerovo: Kuzbassvuzizdat Publ., 2010. 288 p.
6. Lebedev V.P. Klinicheskaya fitoterapiya: Nauchnoe izdanie [Clinical Herbal Medicine: Scientific publication]. Novosibirsk, 2003. 368 p.
7. Lobach E.Yu., Galikaeva O.O., Gur'yanov Yu.G., and Poznyakovskiy V.M. Merchandizing characterization and functional orientation of new specialized product. Stock manager, 2015, no. 5-6, pp. 6-9. (In Russian).
8. Lobach E.Yu., Galikaeva O.O., Gur'yanov Yu.G., and Poznyakovskiy V.M. Technology development and research of consumer properties of biologically active additives based on pantogematogena. Engineering and technology of food production, 2014, no. 3, pp. 132-135. (In Russian).
9. Lobach E.Yu., Avstrievskikh A.N., and Poznyakovskiy V.M. New energy complex based on algae: efficacy and functional orientation. Stock manager, 2015, no. 12, pp. 15-18. (In Russian).
10. Lobach E.Yu., Vekovtsev A.A., Fesikova P.V., and Poznyakovskiy V.M. Clinical testing of specialized products for dietary. Engineering and technology of food production, 2015, no. 3, pp. 109-115. (In Russian).
11. Metodicheskie rekomendatsii MR2.3.1.2432-08. Normy fiziologicheskoy potrebnosti v energii i pishchevykh veshchestvakh dlya razlichnykh grupp naseleniya Rossiyskoy Federatsii [Guidelines MR2.3.1.2432-08. Norms of physiological energy and nutrient requirements of various groups of the population of the Russian Federation].
12. Poznyakovskiy V.M., Gur'yanov Yu.G., and Bebenin V.V. Pishchevye i biologicheski aktivnye dobavki: kharakteristika, primenenie, kontrol' [Food and dietary supplements: characteristics, application control]. Kemerovo: Kuzbassvuzizdat Publ., 2011. 275 p.
13. Rasporyazhenie Pravitel'stva Rossiyskoy Federatsii ot 25.10.10 goda № 1873-r «Osnovy gosudarstvennoy politiki Rossiyskoy Federatsii v oblasti zdorovogo pitaniya naseleniya na period do 2020 goda» [Order of the Russian Federation no. 1873-r from October 25, 2010. Fundamentals of Russian state policy in the field of healthy nutrition for the period till 2020].
14. Spirichev V.B., Shantyuk L.N. and Poznyakovskiy V.M. Obogashchenie pishchevykh produktov vitaminami i mineral'nymi veshchestvami. Nauka i tekhnologiya [Food fortification with vitamins and minerals. Science and Technology]. Novosibirsk: Sib. Univ. Publ., 2005. 548 p.
15. Strategiya razvitiya pishchevoy i pererabatyvayushchey promyshlennosti Rossiyskoy Federatsii do 2020 goda: rasporyazhenie Pravitel'stva Rossiyskoy Federatsii ot 17.04.12 goda № 559-r [Development strategy of food and processing industry of the Russian Federation till 2020: the disposal of the Russian Federation no. 559-p from April 17, 2012]. Reference legal system “Garant”. Garant-Servis. (In Russian).
16. Tekhnicheskiy reglament TS 027/2012 «O bezopasnosti otdel'nykh vidov spetsializirovannoy pishchevoy produktsii, v tom chisle dieticheskogo, lechebnogo i dieticheskogo profilakticheskogo pitaniya» [Technical regulation CU 027/2012. On the safety of certain types of specialized food products, including dietary, medical and dietary preventive nutrition]. Board of the Eurasian Economic Commission, June 15, 2012, no. 34, 26 p.
17. Tutel'yan V.A., Spirichev V.B., Sukhanov B.P., and Kudasheva V.A. Mikronutrienty v pitanii zdorovogo i bol'nogo cheloveka [Micronutrients in the diet of healthy and sick person]. Moscow: Kolos Publ., 2002. 424 p.
18. Tutel'yan V.A., Belousov Yu.B., and Gurevich K.G. Bezopasnost' i effektivnost' biologicheski aktivnykh veshchestv rastitel'nogo proiskhozhdeniya [The safety and efficacy of bioactive substances of vegetable origin: a monograph]. Novosibirsk: Ekor-Kniga Publ, 2007. 316 p.
19. Whiting S.J. and Barabash W.A. Dietary reference intakes for micronutrients: considerations for physical activity. Applied Physiology, Nutrition, and Metabolism, 2006, vol. 31, pp. 80-85. DOI: 10.1139/h05-021.
20. Silberglitt R., Antón P.S., Howell D.R., et al. The Global Technology Revolution 2020, In-Depth Analysi: Bio/Nano/Materials Information Technology Trends, Drivers, Barriers, and Social Implications, Santa Monica, CA: RAND Corporation (MG-475), 2006.