ISSN 2308-4057 (Print),
ISSN 2310-9599 (Online)

Effect of Multicomponent Cereal Mixtures on Glucose Level in Blood of Experimental Animals

Abstract
Recipes of multicomponent mixtures of cereals with proteins of high biological value were developed. In experiments, 35 adult male Wistar rats were used. Prior to the experiment, all animals were fed with powdered milk, grain or grain waste, germinated oats, and comprehensive multivitamin preparations, in addition to the standard balanced diet. Against this background, blood was collected from the animals for biochemical studies (control group, n = 20). Blood collection from tail vein was performed under general anesthesia, according to the recommendations of the Federation of European Laboratory Animal Science Working Group. Animals were fed with viscous-texture porridge made from ternary mixtures (rice, peas, and buckwheat; rice, barley, and maize) and the five-component cereals (rice, barley, maize, buckwheat, and peas) for 30 days. The control group received a standard vivarium diet. Postprandial glycemic curves in all groups were compared with the response to administration of glucose in the amount corresponding to the diet carbohydrates content. Postprandial glycemia was significantly lower in all groups of animals receiving the experimental diets than in the group of animals who received aqueous solution of glucose directly in the stomach by gavage at the rate of 0.03 g/g total weight (glucose tolerance test, GTT). Baudouin hyperglycemic factor was 1.52 for the control group, and in the range of 1.07–1.10, for the experimental groups. The glycemic index was 76.2 and 53.6–55.9, respectively. The results evidence that the products prepared from multicomponent mixtures of cereals belong to the products with low glycemic index
Keywords
multicomponent mixtures of cereals, postprandial glycemia, glycemic index
REFERENCES
  1. Lobykina, E.N., Koltun, V.Z., and Khvostova, O.I., Glycemic index of products and its application in dietary therapy of obesity, Voprosy pitaniya (Nutrition Issues), 2007, vol. 76, no. 1, pp. 14–22.
  2. Jenkins, D.J.A., Wolewer, T.M.S., and Jenkins, A.L., The Glycaemic Response to Carbohydrate Foods, Lancet, 1984, vol. 2, pp. 388–391.
  3. Vloshchinskii, P.E., and Kolpakov, A.R., Structure of nutrition and glucose tolerance in the northerns, Tekhnika i tekhnologiya pishchevykh proizvodstv (Methods and Technology of Food Production), 2011, pp. 17–21.
  4. Jenkins, D.J.A., Lente Carbohydrate: A Newer Approach to the Dietary Management of Diabetes, Diabetes Care, 1982, no. 5, pp. 634–641.
  5. Jenkins, D.J.A., Wolever, T.M.S., Jenkins, A.L., et al., The Glycaemic Index of Foods Tested in Diabetic Patients: A New Basis for Carbohydrate Exchange Favouring the Use of Legumes, Diabetologia, 1983, no. 24, pp. 257–264.
  6. Jenkins, D.J.A., and Jenkins, A.L., The Glycemic Index, Fiber, and the Dietary Treatment of Hypertriglyceridemia and Diabetes, J. Am. Coll. Nutr., 1987, vol. 6, no. 1, pp. 11–17.
  7. Jenkins, A.L., Kacinik, V., Lyon, M., and Wolever, T.M.S., Effect of Adding the Novel Fiber, PGX, to Commonly Consumed Foods on Glycemic Response, Glycemic Index and GRIP: A Simple and Effective Strategy for Reducing Post Prandial Blood Glucose Levels – A Randomized, Controlled Trial, Nutrition J., 2010, vol. 9, p. 58.
  8. Kendysh, I.N., Regulyatsyya uglevodnogo obmena (Regulation of Carbohydrate Exchange), Moscow: Meditsyna, 1985.
  9. Newsholme, E., and Start, C., Regulation in Metabolism, New York and London: John Wiley and Sons, 1973.
  10. Kopaladze, R.E., Regulation of animal experiments: Ethics, laws, and alternatives, Uspekhi physiol. nauk (Progress in Physiology Sciences), 1998, vol. 29, no. 4, pp. 74–92.
  11. Kovalev, N.I., Kartseva, N.N., and Krasnova, N.S., Ways to increased biological values of food products and cooled meals, in Puti snizheniya poter´ pishchevykh produktov pri khranenii i sovershenstvoveniya tekhnologii producktov obshchestvennogo pitaniya (Methods to Decrease Losses of Food Products upon Storage and Improvement of Public Food Service Product Technology), Leningrad, 1982, pp. 160–173.
  12. Nasanova, O.N., Effect of water extracts of common nettle, common burdock, dandelion, and common goat’s rue on hyperglycemia and hyperlipidemia upon diabetes mellitus type 2, Bulleten´ sibirskoi meditsyny (Bulletin of the Siberian Medicine), 2011, no. 3, pp. 87–90.
  13. Agarkov, D.Yu., et al., Hypoglycemic properties of the extract of Gymnema sylvestre, Vestnik VolGMU (Bulletin of the Volgograd State Medical University), 2007, no. 1 (21), pp. 79–82.
  14. Volchegorskiim I.A., Rassokhina, L.M., and Miroshnichenko, I.Yu., Insulin-potentiating effects of antioxidants in experimental diabetes mellitus, Problemy endokrinologii (Problems of Endocrinilogy), 2010, no. 2, pp. 27–35.
  15. Selyatitskaya, V.G., Palçhikova, N.A., and Kuznetsova, N.V., Activity of adrenocortical system in rats with high and low resistance to diabetogenic effect of alloxan, Fundamental´nye issledovaniya (Fundamental Studies), 2011, no. 3, pp. 142–147.
  16. American Diabetes Association. Nutrition recommendations and interventions for diabetes: a position statement of the American Diabetes Association, Diabetes Care, 2008, no. 31, suppl. 1, pp. 61–78.
How to quote?
About journal

Download
Contents
Abstract
Keywords
References